Rat DIO3 (Deiodinase, Iodothyronine, Type III) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014818)

Rat DIO3 (Deiodinase, Iodothyronine, Type III) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014818)

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STJE0014818
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.117ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This DIO3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Dio3
Gene ID: 29475
Uniprot ID: IOD3_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Neonatal skin, placenta, skeletal muscle and cerebral cortex.
Post Translational Modifications
Function Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Protein Name Thyroxine 5-Deiodinase
5diii
Dioiii
Type 3 Di
Type Iii Iodothyronine Deiodinase
Database Links Reactome: R-RNO-350864
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Endosome Membrane
Alternative ELISA Names Thyroxine 5-Deiodinase ELISA kit
5diii ELISA kit
Dioiii ELISA kit
Type 3 Di ELISA kit
Type Iii Iodothyronine Deiodinase ELISA kit
Dio3 ELISA kit
Itdi3 ELISA kit
Txdi3 ELISA kit
output

Information sourced from Uniprot.org

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