Rat CXCR3 (CXC-Chemokine Receptor 3) CLIA Kit for Quantitative Detection

Name: Rat CXCR3 (CXC-Chemokine Receptor 3) CLIA Kit for Quantitative Detection
SKU: STJC0001639
Availability: InStock

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SPECIFICATIONS

STJC0001639

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Short Description	This rat CXCR3 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications	CLIA
Reactivity	Rat
Sensitivity	18.75pg/mL
Detection Limit	31.25~2000pg/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Chemiluminescence

Gene Symbol	Cxcr3
Gene ID	84475
Uniprot ID	CXCR3_RAT
Specificity	This kit recognizes Rat CXCR3 in samples. No significant cross-reactivity or interference between Rat CXCR3 and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Post Translational Modifications	Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated.
Function	Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling.
Protein Name	C-X-C Chemokine Receptor Type 3 Cxc-R3 Cxcr-3 Interferon-Inducible Protein 10 Receptor Ip-10 Receptor Cd Antigen Cd183
Database Links	Reactome: R-RNO-380108 Reactome: -RNO-418594
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative CLIA Names	C-X-C Chemokine Receptor Type 3 CLIA kit Cxc-R3 CLIA kit Cxcr-3 CLIA kit Interferon-Inducible Protein 10 Receptor CLIA kit Ip-10 Receptor CLIA kit Cd Antigen Cd183 CLIA kit Cxcr3 CLIA kit
Specificity	This kit recognizes Rat CXCR3 in samples. No significant cross-reactivity or interference between Rat CXCR3 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	95.08	278.50	930.30	102.10	277.96	944.41
Standard deviation	10.08	21.89	84.29	11.61	29.44	103.41
CV (%)	10.60	7.86	9.06	11.37	10.59	10.95