Tissue Specificity | Expressed in the brain, adrenal medulla and anterior pituitary. In the brain, localized to the hippocampal formation, the endocrine hypothalamus, the olfactory system, and in anatomically distinct structures in the pons-medulla. |
Post Translational Modifications | Extensively processed in glucagonoma tissue by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. The proglucagon-converting enzymes present in transformed alpha-cells are likely candidates to be involved in tissue-specific processing. |
Function | Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. |
Protein Name | Secretogranin-1Chromogranin-BCgbGlucagonoma PeptideSecretogranin-ISgi Cleaved Into - Pe-11 - Ccb Peptide Short Form - Ccb Peptide Long Form |
Database Links | Reactome: R-RNO-381426Reactome: -RNO-8957275 |
Cellular Localisation | SecretedNeuroendocrine And Endocrine Secretory Granules |
Alternative ELISA Names | Secretogranin-1 ELISA kitChromogranin-B ELISA kitCgb ELISA kitGlucagonoma Peptide ELISA kitSecretogranin-I ELISA kitSgi Cleaved Into - Pe-11 - Ccb Peptide Short Form - Ccb Peptide Long Form ELISA kitChgb ELISA kit |
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Information sourced from Uniprot.org