| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes. |
| Protein Name | Atp Synthase-Coupling Factor 6 - MitochondrialAtpase Subunit F6Atp Synthase Peripheral Stalk Subunit F6 |
| Database Links | Reactome: R-RNO-163210Reactome: -RNO-8949613Reactome: -RNO-9837999 |
| Cellular Localisation | MitochondrionMitochondrion Inner Membrane |
| Alternative ELISA Names | Atp Synthase-Coupling Factor 6 - Mitochondrial ELISA kitAtpase Subunit F6 ELISA kitAtp Synthase Peripheral Stalk Subunit F6 ELISA kitAtp5pf ELISA kitAtp5j ELISA kit |
| output | |
Information sourced from Uniprot.org
