Rat a2M (Alpha-2-Macroglobulin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013172)

Rat a2M (Alpha-2-Macroglobulin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013172)

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STJE0013172
£435.50 - £594.50
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 8.7ng/mL
Detection Limit: 15.6-1000ng/mL
Short Description : This a2M Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, urine or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: A2m
Gene ID: 24153
Uniprot ID: A2MG_RAT
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, urine or other biological fluids.
Tissue Specificity Highest constitutive expression in ovary. Low level in testis, uterus and non-acute phase liver. Protein found in plasma.
Post Translational Modifications
Function Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Protein Name Alpha-2-Macroglobulin
Alpha-2-M
Database Links Reactome: R-RNO-114608
Reactome: -RNO-140837
Reactome: -RNO-1474228
Reactome: -RNO-8963896
Cellular Localisation Secreted
Alternative ELISA Names Alpha-2-Macroglobulin ELISA kit
Alpha-2-M ELISA kit
A2m ELISA kit
A2m1 ELISA kit
output

Information sourced from Uniprot.org

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