Recombinant Antibodies

Primary Antibodies

Recombinant Antibodies

Recombinant antibodies, or rAbs, are monoclonal antibodies created in vitro using synthetic genes. Their main advantage is not needing animals or hybridomas to be produced, making them more humane and efficient compared to traditional monoclonal antibodies.

Browse all recombinant antibodies
Product overview

What are recombinant antibodies?

St John's Laboratory lists over 260 recombinant antibodies, produced using synthetic gene technology rather than through animal immunisation.

  • Produced without animals or hybridomas Because the antibody gene is synthesised and cloned directly, recombinant antibodies do not require an animal to be immunised or a hybridoma cell line to be maintained.
  • Consistent from batch to batch Since every recombinant antibody is expressed from the same defined genetic sequence, each production run closely matches the last, reducing lot-to-lot variation.
  • Monoclonal by nature Every recombinant antibody listed here is monoclonal, since the cloned gene encodes a single, defined antibody sequence rather than a mixed population.
Production process

How recombinant antibodies are made

Producing a recombinant antibody starts with synthesising the genetic sequence that encodes the antibody of interest, rather than raising it in a live animal. That synthetic gene is then cloned into an expression vector and introduced into a host cell line, which is cultured to manufacture the antibody at scale.

Featured hosts

Featured hosts

Recombinant antibodies on this page are expressed using a mix of animal-derived and cell-line host systems. The host listed for a given product refers to the expression system used, rather than an animal that was immunised.

Mouse Rabbit Human CHO cells

Need help choosing an antibody?

Contact our technical support team for help selecting an antibody for your target of interest. Each product page includes a downloadable datasheet and SDS, with dispatch on overnight priority shipping with gel ice packs.

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