Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Phospho-PGCA Blocking Peptide is synthetically produced from the 500-550 sequence and is suitable for use in western blot applications. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
NPR1 |
Gene ID: |
4881 |
Uniprot ID: |
ANPRA_HUMAN |
Immunogen Region: |
500-550 |
Immunogen: |
Synthetic peptide taken within amino acid region 500-550 on human Atrial natriuretic peptide receptor 1 protein. |
Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
Peptide Name | Atrial Natriuretic Peptide Receptor 1Atrial Natriuretic Peptide Receptor Type AAnp-AAnpr-ANpr-AGuanylate Cyclase AGc-A |
Database Links | Reactome: R-HSA-5578768 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 1 proteinAtrial Natriuretic Peptide Receptor Type A proteinAnp-A proteinAnpr-A proteinNpr-A proteinGuanylate Cyclase A proteinGc-A proteinNPR1 proteinANPRA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance