| Short Description : | PDE4B1 Positive Control for STJ502307 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | WB: 1:500 |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Pde4b |
| Gene ID: | 24626 |
| Uniprot ID: | PDE4B_RAT |
| Specificity: | This is positive control is recommended for use in combination with PDE4B1 antibody STJ502307. |
| Tissue Specificity | Widely expressed. Isoform 3: Expressed in brain, heart, lung and liver. Isoform 4: Expressed in liver and brain. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Peptide Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4bDpde4Camp-Specific Phosphodiesterase 4b |
| Database Links | Reactome: R-RNO-180024 |
| Cellular Localisation | Isoform 4: CytoplasmCell Membrane |
| Alternative Peptide Names | 3' -5'-Cyclic-Amp Phosphodiesterase 4b proteinDpde4 proteinCamp-Specific Phosphodiesterase 4b proteinPde4b protein |
Information sourced from Uniprot.org