Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. |
Peptide Name | Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1Hematopoietic Pbx-Interacting Protein |
Cellular Localisation | CytoplasmCytoskeletonNucleusShuttles Between The Nucleus And The CytosolMainly Localized In The CytoplasmAssociated With MicrotubulesDetected In Small Amounts In The Nucleus |
Alternative Peptide Names | Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1 proteinHematopoietic Pbx-Interacting Protein proteinPbxip1 proteinHpip protein |
Information sourced from Uniprot.org