PBR Blocking Peptide peptide (STJ505045)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to unique amino acid sequence on 18 kDa mitochondrial benzodiazepine receptor protein.
General Information
| Short Description | PBR Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPO |
| Gene ID | 706 |
| Uniprot ID | TSPO_HUMAN |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on 18 kDa mitochondrial benzodiazepine receptor protein. |
Additional Info
| Tissue Specificity | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Peptide Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Translocator Protein proteinMitochondrial Benzodiazepine Receptor proteinPkbs proteinPeripheral-Type Benzodiazepine Receptor proteinPbr proteinTSPO proteinBZRP proteinMBR protein |
Information sourced from Uniprot.org