| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | P2Y1 Positive Control for STJ502038 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | P2ry1 |
| Gene ID: | 25265 |
| Uniprot ID: | P2RY1_RAT |
| Specificity: | This is positive control is recommended for use in combination with P2Y1 antibody STJ502038. |
| Tissue Specificity | Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis. |
| Function | Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. |
| Peptide Name | P2y Purinoceptor 1P2y1Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-RNO-416476Reactome: -RNO-417957Reactome: -RNO-418592 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | P2y Purinoceptor 1 proteinP2y1 proteinAtp Receptor proteinPurinergic Receptor proteinP2ry1 protein |
Information sourced from Uniprot.org
