Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
ORP150 Blocking Peptide is synthetically produced from the 950-999 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
HYOU1 |
Gene ID: |
10525 |
Uniprot ID: |
HYOU1_HUMAN |
Immunogen Region: |
950-999 |
Immunogen: |
Synthetic peptide taken within amino acid region 950-999 on human Hypoxia up regulated 1. |
Tissue Specificity | Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers. |
Function | Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. |
Peptide Name | Hypoxia Up-Regulated Protein 1150 Kda Oxygen-Regulated ProteinOrp-150170 Kda Glucose-Regulated ProteinGrp-170 |
Database Links | Reactome: R-HSA-3000484Reactome: R-HSA-381038 |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative Peptide Names | Hypoxia Up-Regulated Protein 1 protein150 Kda Oxygen-Regulated Protein proteinOrp-150 protein170 Kda Glucose-Regulated Protein proteinGrp-170 proteinHYOU1 proteinGRP170 proteinORP150 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance