| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Phospho-NT5C2 Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | NT5C2 |
| Gene ID: | 22978 |
| Uniprot ID: | 5NTC_HUMAN |
| Immunogen: | Synthetic peptide corresponding to unique amino acid sequences on cNII protein with phosphorylated Serine 7. |
| Tissue Specificity | Widely expressed. |
| Function | Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. |
| Peptide Name | Cytosolic Purine 5'-Nucleotidase Cytosolic 5'-Nucleotidase Ii Cn-Ii Cytosolic Imp/Gmp-Specific 5'-Nucleotidase Cytosolic Nucleoside Phosphotransferase 5'N High Km 5'-Nucleotidase |
| Database Links | Reactome: R-HSA-2161541 Reactome: R-HSA-74259 Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm Cytosol |
| Alternative Peptide Names | Cytosolic Purine 5'-Nucleotidase protein Cytosolic 5'-Nucleotidase Ii protein Cn-Ii protein Cytosolic Imp/Gmp-Specific 5'-Nucleotidase protein Cytosolic Nucleoside Phosphotransferase 5'N protein High Km 5'-Nucleotidase protein NT5C2 protein NT5B protein NT5CP protein PNT5 protein |
Information sourced from Uniprot.org