| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
NT5C2 Blocking Peptide for STJ500602 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
NT5C2 |
| Gene ID: |
22978 |
| Uniprot ID: |
5NTC_HUMAN |
| Specificity: |
This blocking peptide is recommended for use in combination with NT5C2 antibody, STJ500602 |
| Immunogen: |
Synthetic peptide corresponding to unique aino acid sequence on human cNII protein. |
| Tissue Specificity | Widely expressed. |
| Function | Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. |
| Peptide Name | Cytosolic Purine 5'-NucleotidaseCytosolic 5'-Nucleotidase IiCn-IiCytosolic Imp/Gmp-Specific 5'-NucleotidaseCytosolic Nucleoside Phosphotransferase 5'NHigh Km 5'-Nucleotidase |
| Database Links | Reactome: R-HSA-2161541Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Peptide Names | Cytosolic Purine 5'-Nucleotidase proteinCytosolic 5'-Nucleotidase Ii proteinCn-Ii proteinCytosolic Imp/Gmp-Specific 5'-Nucleotidase proteinCytosolic Nucleoside Phosphotransferase 5'N proteinHigh Km 5'-Nucleotidase proteinNT5C2 proteinNT5B proteinNT5CP proteinPNT5 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
