| Tissue Specificity | Widely expressed. |
| Function | Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. |
| Peptide Name | Cytosolic Purine 5'-NucleotidaseCytosolic 5'-Nucleotidase IiCn-IiCytosolic Imp/Gmp-Specific 5'-NucleotidaseCytosolic Nucleoside Phosphotransferase 5'NHigh Km 5'-Nucleotidase |
| Database Links | Reactome: R-HSA-2161541Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Peptide Names | Cytosolic Purine 5'-Nucleotidase proteinCytosolic 5'-Nucleotidase Ii proteinCn-Ii proteinCytosolic Imp/Gmp-Specific 5'-Nucleotidase proteinCytosolic Nucleoside Phosphotransferase 5'N proteinHigh Km 5'-Nucleotidase proteinNT5C2 proteinNT5B proteinNT5CP proteinPNT5 protein |
Information sourced from Uniprot.org
