| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | NPY2R Positive Control for STJ501965 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | NPY2R |
| Gene ID: | 4887 |
| Uniprot ID: | NPY2R_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with NPY2R antibody STJ501965. |
| Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > Ile-31, Gln-34 PP > Leu-31, Pro-34 NPY > PP, Pro-34 PYY and NPY free acid. |
| Peptide Name | Neuropeptide Y Receptor Type 2Npy2-RNpy-Y2 ReceptorY2 Receptor |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Neuropeptide Y Receptor Type 2 proteinNpy2-R proteinNpy-Y2 Receptor proteinY2 Receptor proteinNPY2R protein |
Information sourced from Uniprot.org