Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > Ile-31, Gln-34 PP > Leu-31, Pro-34 NPY > PP, Pro-34 PYY and NPY free acid. |
Peptide Name | Neuropeptide Y Receptor Type 2Npy2-RNpy-Y2 ReceptorY2 Receptor |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | Neuropeptide Y Receptor Type 2 proteinNpy2-R proteinNpy-Y2 Receptor proteinY2 Receptor proteinNPY2R protein |
Information sourced from Uniprot.org