Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Nkx22 Blocking Peptide is synthetically produced from the 200-273 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | NKX2-2 |
Gene ID: | 4821 |
Uniprot ID: | NKX22_HUMAN |
Immunogen Region: | 200-273 |
Immunogen: | C-epitope synthetic peptide taken within amino acid region 200-273 on human homeobox protein Nkx-2.2 |
Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. |
Peptide Name | Homeobox Protein Nkx-2.2 Homeobox Protein Nk-2 Homolog B |
Database Links | Reactome: R-HSA-210745 Reactome: R-HSA-210746 |
Cellular Localisation | Nucleus |
Alternative Peptide Names | Homeobox Protein Nkx-2.2 protein Homeobox Protein Nk-2 Homolog B protein NKX2-2 protein NKX2.2 protein NKX2B protein |
Information sourced from Uniprot.org