Myeloperoxidase Blocking Peptide peptide (STJ504378)

SKU:
STJ504378-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Myeloperoxidase Blocking Peptide is synthetically produced from the 580-630 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MPO
Gene ID: 4353
Uniprot ID: PERM_HUMAN
Immunogen Region: 580-630
Immunogen: Synthetic peptide taken within amino acid region 580-630 human Myeloperoxidase protein.
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.
Peptide Name Myeloperoxidase
Mpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8941413
Cellular Localisation Lysosome
Alternative Peptide Names Myeloperoxidase protein
Mpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain protein
MPO protein

Information sourced from Uniprot.org

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