| Tissue Specificity | Highly expressed in kidney and lung. Lower levels in heart, brain, spleen, liver, skeletal muscle and testis. Expressed in low metastatic melanoma cells. |
| Post Translational Modifications | |
| Function | Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. Suppresses tumor growth in vivo. |
| Protein Name | Ccn Family Member 4Elm-1Wnt1-Inducible-Signaling Pathway Protein 1Wisp-1 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Ccn Family Member 4 ELISA kitElm-1 ELISA kitWnt1-Inducible-Signaling Pathway Protein 1 ELISA kitWisp-1 ELISA kitCcn4 ELISA kitElm1 ELISA kitWisp1 ELISA kit |
| output | |
Information sourced from Uniprot.org