Tissue Specificity | Plasma. |
Post Translational Modifications | Sulfated on tyrosine residues. N- and O-glycosylated. It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
Function | Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. |
Protein Name | VitronectinVnS-ProteinSerum-Spreading Factor |
Database Links | Reactome: R-MMU-2129379Reactome: -MMU-216083Reactome: -MMU-3000170Reactome: -MMU-3000178Reactome: -MMU-977606 |
Cellular Localisation | SecretedExtracellular Space |
Alternative ELISA Names | Vitronectin ELISA kitVn ELISA kitS-Protein ELISA kitSerum-Spreading Factor ELISA kitVtn ELISA kit |
output | |
Information sourced from Uniprot.org