Mouse VSIR/VISTA protein (Recombinant) (C-His) (STJP014038)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
STJP014038-100
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General Information

Short DescriptionRecombinant-Mouse VSIR/VISTA-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolVsir
Gene ID74048
Uniprot IDVISTA_MOUSE
ImmunogenMus musculus (Mouse)
Immunogen RegionPhe33-Ala191

Additional Info

Post Translational Modifications At the cell surface, may be cleaved by MMP14. N-glycosylated.
Function Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.
Protein Name V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation
Platelet Receptor Gi24
V-Set Domain-Containing Immunoregulatory Receptor
V-Set Immunoregulatory Receptor
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation protein
Platelet Receptor Gi24 protein
V-Set Domain-Containing Immunoregulatory Receptor protein
V-Set Immunoregulatory Receptor protein
Vsir protein
Dies1 protein
PD-1H protein
VISTA protein

Information sourced from Uniprot.org

Citations

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