Tissue Specificity | Abundantly expressed in spleen, placenta, skeleton muscle, lung and brain. |
Post Translational Modifications | N-glycosylated. Phosphorylated by PKA. |
Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF1, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius.is not activated by vanilloids and acidic pH. |
Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 2Trpv2Growth Factor-Regulated Calcium ChannelGrcOsm-9-Like Trp Channel 2Otrpc2 |
Database Links | Reactome: R-MMU-3295583 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmMelanosomeTranslocates From The Cytoplasm To The Plasma Membrane Upon Ligand Stimulation |
Alternative ELISA Names | Transient Receptor Potential Cation Channel Subfamily V Member 2 ELISA kitTrpv2 ELISA kitGrowth Factor-Regulated Calcium Channel ELISA kitGrc ELISA kitOsm-9-Like Trp Channel 2 ELISA kitOtrpc2 ELISA kitTrpv2 ELISA kitGrc ELISA kit |
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Information sourced from Uniprot.org