| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Tnfrsf9 |
| Gene ID: | 21942 |
| Uniprot ID: | TNR9_MOUSE |
| Immunogen Region: | Val24-Leu211 |
| Immunogen: | Recombinant Mouse TNFRSF9/4-1BB/CD137 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Leu211) of mouse TNFRSF9/4-1BB/CD137 (Accession #NP_001070976.1) fused with a 6×His tag at the C-terminu |
| Immunogen Sequence: | VQNSCDNCQPGTFCRKYNPV CKSCPPSTFSSIGGQPNCNI CRVCAGYFRFKKFCSSTHNA ECECIEGFHCLGPQCTRCEK DCRPGQELTKQGCKTCSLGT FNDQNGTGVCRPWTNCSLDG RSVLKTGTTEKDVVCGPPVV SFSPSTTISVTPEGGPAFKK TTGAAQEEDACSCRCPQEEE GGGGGYEL |
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorT-Cell Antigen 4-1bbCd Antigen Cd137 |
| Database Links | Reactome: R-MMU-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein4-1bb Ligand Receptor proteinT-Cell Antigen 4-1bb proteinCd Antigen Cd137 proteinTnfrsf9 proteinCd137 proteinIla proteinLy63 protein |
Information sourced from Uniprot.org