Mouse TNFRSF18/GITR/CD357 protein (Recombinant) (C-His) (STJP020302)

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STJP020302-100
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: Tnfrsf18
Gene ID: 21936
Uniprot ID: TNR18_MOUSE
Immunogen Region: Ser22-His153
Immunogen: Recombinant Mouse TNFRSF18/GITR/CD357 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser22-His153) of mouse TNFRSF18/GITR/CD357 (Accession #Q8C4K3) fused with His tag at the C-terminus.
Tissue Specificity Preferentially expressed in activated T lymphocytes.
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 18
Glucocorticoid-Induced Tnfr-Related Protein
Cd Antigen Cd357
Database Links Reactome: R-MMU-5669034
Cellular Localisation Isoform A: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform B: Cell Membrane
Isoform C: Cell Membrane
Isoform D: Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 18 protein
Glucocorticoid-Induced Tnfr-Related Protein protein
Cd Antigen Cd357 protein
Tnfrsf18 protein
Gitr protein

Information sourced from Uniprot.org