Mouse TNC/Tenascin protein (Recombinant) (N-His) (STJP009886)

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STJP009886
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse TNC/Tenascin-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Tnc
Gene ID: 21923
Uniprot ID: TENA_MOUSE
Immunogen Region: Pro1888-Ala2110
Immunogen: Mus musculus (Mouse)
Post Translational Modifications N-glycosylated.
Function Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins ITGA8:ITGB1, ITGA9:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells.
Protein Name Tenascin
Tn
Hexabrachion
Tenascin-C
Tn-C
Database Links Reactome: R-MMU-216083
Reactome: -MMU-3000178
Reactome: -MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Tenascin protein
Tn protein
Hexabrachion protein
Tenascin-C protein
Tn-C protein
Tnc protein
Hxb protein

Information sourced from Uniprot.org

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