| Tissue Specificity | |
| Post Translational Modifications | Substrate of different protein kinases. Phosphorylation, including phosphorylation at Ser-9, promotes synapsin-1 dissociation from synaptic vesicles, regulates its rate of dispersion, and controls the kinetics of vesicle pool turnover. |
| Function | Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxide functions at a presynaptic level. |
| Protein Name | Synapsin-1Synapsin I |
| Database Links | Reactome: R-MMU-181429Reactome: -MMU-212676 |
| Cellular Localisation | SynapseGolgi ApparatusPresynapseCytoplasmic VesicleSecretory VesicleSynaptic VesicleDissociates From Synaptic Vesicles And Redistributes Into The Axon During Action Potential FiringIn A Step That Precedes Fusion Of Vesicles With The Plasma MembraneReclusters To Presynapses After The Cessation Of Synaptic Activity |
| Alternative ELISA Names | Synapsin-1 ELISA kitSynapsin I ELISA kitSyn1 ELISA kitSyn-1 ELISA kit |
| output | |
Information sourced from Uniprot.org
