Mouse SFRP4 protein (Recombinant) (N-His-SUMO) (STJP009222)

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STJP009222
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse SFRP4-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Sfrp4
Gene ID: 20379
Uniprot ID: SFRP4_MOUSE
Immunogen Region: Glu25-Asn116
Immunogen: Mus musculus (Mouse)
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Protein Name Secreted Frizzled-Related Sequence Protein 4
Frp-4
Sfrp-4
Cellular Localisation Secreted
Alternative Protein Names Secreted Frizzled-Related Sequence Protein 4 protein
Frp-4 protein
Sfrp-4 protein
Sfrp4 protein

Information sourced from Uniprot.org