Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
Protein Name | Secreted Frizzled-Related Sequence Protein 4Frp-4Sfrp-4 |
Cellular Localisation | Secreted |
Alternative Protein Names | Secreted Frizzled-Related Sequence Protein 4 proteinFrp-4 proteinSfrp-4 proteinSfrp4 protein |
Information sourced from Uniprot.org