| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse SFRP4-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Sfrp4 |
| Gene ID: | 20379 |
| Uniprot ID: | SFRP4_MOUSE |
| Immunogen Region: | Glu25-Asn116 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Protein Name | Secreted Frizzled-Related Sequence Protein 4Frp-4Sfrp-4 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secreted Frizzled-Related Sequence Protein 4 proteinFrp-4 proteinSfrp-4 proteinSfrp4 protein |
Information sourced from Uniprot.org