| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Mouse SFRP2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to compete with Frizzled-1 for binding to biotinylated Wnt-3a. The IC50 value is 0.7-3.5 nM, under conditions in which recombinant Mouse Frizzled‑1 is present at 2.1 nM, and biotinylated rmWnt-3a concentration is 2.7 nM. |
| Gene Symbol: | Sfrp2 |
| Gene ID: | 20319 |
| Uniprot ID: | SFRP2_MOUSE |
| Immunogen Region: | Leu25-Cys295 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Protein Name | Secreted Frizzled-Related Protein 2Sfrp-2Protein Sdf5Secreted Apoptosis-Related Protein 1Sarp-1 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secreted Frizzled-Related Protein 2 proteinSfrp-2 proteinProtein Sdf5 proteinSecreted Apoptosis-Related Protein 1 proteinSarp-1 proteinSfrp2 proteinSarp1 proteinSdf5 protein |
Information sourced from Uniprot.org