Tissue Specificity | |
Post Translational Modifications | Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet. |
Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. |
Protein Name | Perilipin-1Lipid Droplet-Associated ProteinPerilipin A |
Database Links | |
Cellular Localisation | Endoplasmic ReticulumLipid DropletLipid Droplet Surface-Associated |
Alternative ELISA Names | Perilipin-1 ELISA kitLipid Droplet-Associated Protein ELISA kitPerilipin A ELISA kitPlin1 ELISA kitPeri ELISA kitPlin ELISA kit |
output | |
Information sourced from Uniprot.org