Mouse Pgp (Permeability Glycoprotein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017825)
SPECIFICATIONS
General Information
| Short Description | This Pgp Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.051ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Abcb1b |
| Gene ID | 18669 |
| Uniprot ID | MDR1B_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Several phosphorylated serine residues are present in the linker domain. |
| Function | Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
| Protein Name | Atp-Dependent Translocase Abcb1Atp-Binding Cassette Sub-Family B Member 1bMultidrug Resistance Protein 1bP-Glycoprotein 1Phospholipid Transporter Abcb1Cd Antigen Cd243 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneCytoplasmAbcb1 Localization Is Influenced By C1orf115 Expression Levels (Plasma Membrane Versus Cytoplasm) |
| Alternative ELISA Names | Atp-Dependent Translocase Abcb1 ELISA kitAtp-Binding Cassette Sub-Family B Member 1b ELISA kitMultidrug Resistance Protein 1b ELISA kitP-Glycoprotein 1 ELISA kitPhospholipid Transporter Abcb1 ELISA kitCd Antigen Cd243 ELISA kitAbcb1b ELISA kitAbcb1 ELISA kitMdr1 ELISA kitMdr1b ELISA kitPgy1 ELISA kitPgy1-1 ELISA kit |
| output |
Information sourced from Uniprot.org