Mouse PEBP1 protein (Recombinant) (N-His) (STJP011111)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse PEBP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | Pebp1 |
| Gene ID | 23980 |
| Uniprot ID | PEBP1_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Met1-Lys187 |
Additional Info
| Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
| Protein Name | Phosphatidylethanolamine-Binding Protein 1Pebp-1Hcnppp Cleaved Into - Hippocampal Cholinergic Neurostimulating PeptideHcnp |
| Database Links | Reactome: R-MMU-5674135Reactome: -MMU-5675221 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Phosphatidylethanolamine-Binding Protein 1 proteinPebp-1 proteinHcnppp Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide proteinHcnp proteinPebp1 proteinPbp proteinPebp protein |
Information sourced from Uniprot.org