| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
| Protein Name | Platelet-Derived Growth Factor Subunit BPdgf Subunit BPdgf-2Platelet-Derived Growth Factor B ChainPlatelet-Derived Growth Factor Beta PolypeptideProto-Oncogene C-Sis |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-1257604Reactome: -MMU-186763Reactome: -MMU-186797Reactome: -MMU-5673001Reactome: -MMU-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Pair Names | Platelet-Derived Growth Factor Subunit B antibody pairPdgf Subunit B antibody pairPdgf-2 antibody pairPlatelet-Derived Growth Factor B Chain antibody pairPlatelet-Derived Growth Factor Beta Polypeptide antibody pairProto-Oncogene C-Sis antibody pairPdgfb antibody pairSis antibody pair |
Information sourced from Uniprot.org