| Tissue Specificity | Liver, kidney, adipose tissue, liver and brain. |
| Post Translational Modifications | Acetylation of Lys-316 is observed in liver mitochondria from fasted mice but not from fed mice. Acetylation of Lys-748 might play a role in catalytic activity regulation. |
| Function | Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. |
| Protein Name | Pyruvate Carboxylase - MitochondrialPyruvic CarboxylasePcb |
| Database Links | |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative ELISA Names | Pyruvate Carboxylase - Mitochondrial ELISA kitPyruvic Carboxylase ELISA kitPcb ELISA kitPc ELISA kitPcx ELISA kit |
| output | |
Information sourced from Uniprot.org
