| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Immunogen Region: | Lys26-Gln115 |
| Immunogen: | Recombinant Mouse Parathormone/PTH Protein is produced by E. coli expression system. The target protein is expressed with sequence (Lys26-Gln115) of mouse Parathormone/PTH (Accession #NM_020623.2) fused with no additional amino acid. |
| Immunogen Sequence: | MPSQMEHAMETMMFTFHKFA GDKGYLTKEDLRVLMEKEFP GFLENQKDPLAVDKIMKDLD QCRDGKVGFQSFFSLIAGLT IACNDYFVVHMKQKGKK |
| Background | Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration inextracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cellsin bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor asparathyroid hormone and has major effects on development. Like most other protein hormones, parathyroidhormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packagedwithin the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secretedas a linear protein of 84 amino acids. |
Information sourced from Uniprot.org