Tissue Specificity | |
Post Translational Modifications | |
Function | Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. |
Protein Name | Platelet-Activating Factor Acetylhydrolase 2 - CytoplasmicPaf -Lysophospholipid TransacetylasePaf -Sphingosine TransacetylasePlatelet-Activating Factor Acetyltransferase Pafah2Serine-Dependent Phospholipase A2Sd-Pla2 |
Database Links | Reactome: R-MMU-418346 |
Cellular Localisation | CytoplasmMembraneLipid-AnchorEndoplasmic Reticulum MembraneIn Resting CellsLocalizes To Intracellular Membranes And CytoplasmTranslocates From The Cytoplasm To Intracellular Membranes Upon Oxidative Stress |
Alternative ELISA Names | Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic ELISA kitPaf -Lysophospholipid Transacetylase ELISA kitPaf -Sphingosine Transacetylase ELISA kitPlatelet-Activating Factor Acetyltransferase Pafah2 ELISA kitSerine-Dependent Phospholipase A2 ELISA kitSd-Pla2 ELISA kitPafah2 ELISA kit |
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Information sourced from Uniprot.org