| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Osmr |
| Gene ID: | 18414 |
| Uniprot ID: | OSMR_MOUSE |
| Immunogen: | Recombinant Mouse OSMR/IL-31RB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu24-Met737) of mouse OSMR (Accession #NP_035149.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | EVLEEPLPLTPEIHKVSFQL KLQEVNLEWTVPALTHEELN MIFQIEISRLNISNTIWVEN YSTTVKREEAVRWNWTSDIP LECVKHFIRIRALVDDTKSL PQSSWGNWSSWKEVNAKVSV EPDKSLIFPKDKVLEEGSNV TICLMYGQNVYNVSCKLQDE PIHGEQLDSHVSLLKLNNVV FLSDTGTNINCQATKGPKRI FGTVLFVSKVLEEPKNVSCE TRDFKTLDCSWEPGVDTTL |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-MMU-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Oncostatin-M-Specific Receptor Subunit Beta proteinInterleukin-31 Receptor Subunit Beta proteinIl-31 Receptor Subunit Beta proteinIl-31r Subunit Beta proteinIl-31r-Beta proteinIl-31rb proteinOsmr proteinOsmrb protein |
Information sourced from Uniprot.org