Mouse NUCB2 protein (Recombinant) (N-His) (STJP011129)

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STJP011129
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse NUCB2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Nucb2
Gene ID: 53322
Uniprot ID: NUCB2_MOUSE
Immunogen Region: Gly51-Leu229
Immunogen: Mus musculus (Mouse)
Function Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Protein Name Nucleobindin-2
Dna-Binding Protein Nefa
Prepronesfatin Cleaved Into - Nesfatin-1
Cellular Localisation Cytoplasm
Perikaryon
Endoplasmic Reticulum
Golgi Apparatus
Nucleus Envelope
Membrane
Peripheral Membrane Protein
Secreted
In Dendrites And Perikarya Of Brain Neurons
Abundant In The Er Cisternae And Nuclear Envelope
But Not Detected In Golgi
Mitochondria Or Nucleoplasm In Neurons
In Cell Culture
Cytoplasmic And Secreted
Nesfatin-1: Secreted
Alternative Protein Names Nucleobindin-2 protein
Dna-Binding Protein Nefa protein
Prepronesfatin Cleaved Into - Nesfatin-1 protein
Nucb2 protein
Nefa protein

Information sourced from Uniprot.org