Tissue Specificity | |
Post Translational Modifications | N-glycosylated. Palmitoylated.this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment. |
Function | G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis. |
Protein Name | Neurotensin Receptor Type 1Nt-R-1Ntr1 |
Database Links | Reactome: R-MMU-375276Reactome: -MMU-416476 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMembrane RaftPalmitoylation Is Required For Localization At Cav1-Enriched Membrane Rafts |
Alternative ELISA Names | Neurotensin Receptor Type 1 ELISA kitNt-R-1 ELISA kitNtr1 ELISA kitNtsr1 ELISA kitNtsr ELISA kit |
output | |
Information sourced from Uniprot.org