Tissue Specificity | Expressed at highest levels in brain, heart and liver, and at lower levels in kidney, colon, skeletal muscle, adrenal gland, ovary and uterus (at protein level). |
Post Translational Modifications | |
Function | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. |
Protein Name | Protein Ndrg2N-Myc Downstream-Regulated Gene 2 ProteinProtein Ndr2 |
Database Links | |
Cellular Localisation | CytoplasmPerinuclear RegionCell ProjectionGrowth ConeIn NeuronsSeems To Concentrate At Axonal Growth ConePerinuclear In Neurons |
Alternative ELISA Names | Protein Ndrg2 ELISA kitN-Myc Downstream-Regulated Gene 2 Protein ELISA kitProtein Ndr2 ELISA kitNdrg2 ELISA kitKiaa1248 ELISA kitNdr2 ELISA kit |
output | |
Information sourced from Uniprot.org