| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Ncr1 |
| Gene ID: | 17086 |
| Uniprot ID: | NCTR1_MOUSE |
| Immunogen: | Recombinant Mouse NCR1/CD335 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln17-Asn255) of mouse NCR1/CD335 (Accession #NP_034876.2) fused with a raFc tag at the C-terminus. |
| Immunogen Sequence: | QRINTEKETLPKPIIWAKPS IMVTNGNSVNIWCQGAQSAS EYQLYFEGSFFALERPKPSR SMNKVRFFISQMTSHTAGIY TCFYQSGELWSKSSNPLKLV VTGLYDTPNLWVYPRPEVTL GENVTFFCQLKTATSKFFLL KERGSNHIQNKYGNIQAEFP MGPVTRAHRGTYRCFGSYND YAWSFPSEPVTLLITGGVEN SSLAPTDPTSSLDYWEFDLS TNESGLQKDSAFWDHTTQN |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Activating Receptor 1Mar-1Lymphocyte Antigen 94Natural Killer Cell P46-Related ProteinNk-P46Nkp46Mnkp46Cd Antigen Cd335 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 1 proteinActivating Receptor 1 proteinMar-1 proteinLymphocyte Antigen 94 proteinNatural Killer Cell P46-Related Protein proteinNk-P46 proteinNkp46 proteinMnkp46 proteinCd Antigen Cd335 proteinNcr1 proteinLy94 protein |
Information sourced from Uniprot.org
