Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 35pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description : | This MSTN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Mstn |
Gene ID: | 17700 |
Uniprot ID: | GDF8_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. |
Post Translational Modifications | Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase. |
Function | Acts specifically as a negative regulator of skeletal muscle growth. |
Protein Name | Growth/Differentiation Factor 8Gdf-8Myostatin |
Database Links | |
Cellular Localisation | Secreted |
Alternative ELISA Names | Growth/Differentiation Factor 8 ELISA kitGdf-8 ELISA kitMyostatin ELISA kitMstn ELISA kitGdf8 ELISA kit |
output |
Information sourced from Uniprot.org