Tissue Specificity | Highly expressed in lung and heart. Expressed at low levels in spleen, liver, kidney and testis. Present in lung (at protein level). |
Post Translational Modifications | Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin. |
Function | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) may potentiate megakaryocyte colony formation. |
Protein Name | MesothelinPre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating FactorMpf - Mesothelin - Cleaved Form |
Database Links | Reactome: R-MMU-163125Reactome: -MMU-381426Reactome: -MMU-8957275 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusMegakaryocyte-Potentiating Factor: Secreted |
Alternative ELISA Names | Mesothelin ELISA kitPre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor ELISA kitMpf - Mesothelin - Cleaved Form ELISA kitMsln ELISA kitMes ELISA kitMpf ELISA kit |
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Information sourced from Uniprot.org