Mouse MIF protein (Recombinant) (His-Tag) (STJP019167)

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STJP019167
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Short Description :Recombinant-Mouse MIF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:Mif
Gene ID:17319
Uniprot ID:MIF_MOUSE
Accession Number:NP_034928
Immunogen:Mouse
Immunogen Region:1-115aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSMPMFIVN TNVPRASVPE GFLSELTQQL AQATGKPAQY IAVHVVPDQL MTFSGTNDPC ALCSLHSIGK IGGAQNRNYS KLLCGLLSDR LHISPDRVYI NYYDMNAANV GWNGSTFA
Function Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Protein Name Macrophage Migration Inhibitory Factor
Mif
Delayed Early Response Protein 6
Der6
Glycosylation-Inhibiting Factor
Gif
L-Dopachrome Isomerase
L-Dopachrome Tautomerase
Phenylpyruvate Tautomerase
Database Links Reactome: R-MMU-202733
Reactome: -MMU-6798695
Cellular Localisation Secreted
Cytoplasm
Does Not Have A Cleavable Signal Sequence And Is Secreted Via A Specialized
Non-Classical Pathway
Secreted By Macrophages Upon Stimulation By Bacterial Lipopolysaccharide (Lps)
Or By M
Tuberculosis Antigens
Alternative Protein Names Macrophage Migration Inhibitory Factor protein
Mif protein
Delayed Early Response Protein 6 protein
Der6 protein
Glycosylation-Inhibiting Factor protein
Gif protein
L-Dopachrome Isomerase protein
L-Dopachrome Tautomerase protein
Phenylpyruvate Tautomerase protein
Mif protein

Information sourced from Uniprot.org

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