| Post Translational Modifications | Hydroxylated on lysine and proline residues within the collagen-like domain. O-glycosylated. O-linked glycans on hydroxylysine residues consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups. |
| Function | Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |
| Protein Name | Mannose-Binding Protein AMbp-AMannan-Binding ProteinRa-Reactive Factor Polysaccharide-Binding Component P28bRarf P28b |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Mannose-Binding Protein A proteinMbp-A proteinMannan-Binding Protein proteinRa-Reactive Factor Polysaccharide-Binding Component P28b proteinRarf P28b proteinMbl1 protein |
Information sourced from Uniprot.org
