| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Sftpd |
| Gene ID: | 20390 |
| Uniprot ID: | SFTPD_MOUSE |
| Immunogen: | Recombinant Mouse Lung surfactant protein D/SFTPD Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala20-Phe374) of mouse SFTPD/SP-D/SFTP4 (Accession #NP_033186.1) fused with a 6×His tag at the C-t |
| Immunogen Sequence: | AEMKSLSQRSVPNTCTLVMC SPTENGLPGRDGRDGREGPR GEKGDPGLPGPMGLSGLQGP TGPVGPKGENGSAGEPGPKG ERGLSGPPGLPGIPGPAGKE GPSGKQGNIGPQGKPGPKGE AGPKGEVGAPGMQGSTGAKG STGPKGERGAPGVQGAPGNA GAAGPAGPAGPQGAPGSRGP PGLKGDRGVPGDRGIKGESG LPDSAALRQQMEALKGKLQR LEVAFSHYQKAALFPDGRS |
| Function | Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
| Protein Name | Pulmonary Surfactant-Associated Protein DPsp-DSp-DLung Surfactant Protein D |
| Database Links | Reactome: R-MMU-166016Reactome: -MMU-198933Reactome: -MMU-391160Reactome: -MMU-5683826Reactome: -MMU-5686938 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixSurface Film |
| Alternative Protein Names | Pulmonary Surfactant-Associated Protein D proteinPsp-D proteinSp-D proteinLung Surfactant Protein D proteinSftpd proteinSftp4 protein |
Information sourced from Uniprot.org