Tissue Specificity | Expressed in the colon, including colonocytes and mucin-containing goblet cells. Not detected in the ileum. |
Post Translational Modifications | |
Function | Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2). Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2. Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism. May be implicated in airway host defense against infection. May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation. |
Protein Name | LactoperoxidaseLpo |
Database Links | Reactome: R-MMU-8941413 |
Cellular Localisation | SecretedCytoplasmExpressed In The Cytoplasm In Intestinal Epithelial Cells |
Alternative ELISA Names | Lactoperoxidase ELISA kitLpo ELISA kitLpo ELISA kit |
output | |
Information sourced from Uniprot.org