Tissue Specificity | Widely expressed with much higher level in brain. Expressed in erythroleukemic cells but not in reticulocytes. |
Post Translational Modifications | |
Function | Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates.converts lysophosphatidylethanolamine to phosphatidylethanolamine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. Converts lysophosphatidylcholine to phosphatidycholine. |
Protein Name | Lysophospholipid Acyltransferase Lpcat41-Acylglycerol-3-Phosphate O-Acyltransferase 71-Agp Acyltransferase 71-Agpat 71-Acylglycerophosphocholine O-Acyltransferase1-Acylglycerophosphoserine O-Acyltransferase1-Alkenylglycerophosphoethanolamine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcyltransferase-Like 3Lysophosphatidylcholine Acyltransferase 4Lysophosphatidylethanolamine Acyltransferase 2Plasmalogen Synthase |
Database Links | Reactome: R-MMU-1482788Reactome: -MMU-1482801Reactome: -MMU-1482839Reactome: -MMU-1482925Reactome: -MMU-1483166 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Lysophospholipid Acyltransferase Lpcat4 ELISA kit1-Acylglycerol-3-Phosphate O-Acyltransferase 7 ELISA kit1-Agp Acyltransferase 7 ELISA kit1-Agpat 7 ELISA kit1-Acylglycerophosphocholine O-Acyltransferase ELISA kit1-Acylglycerophosphoserine O-Acyltransferase ELISA kit1-Alkenylglycerophosphoethanolamine O-Acyltransferase ELISA kit1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kitAcyltransferase-Like 3 ELISA kitLysophosphatidylcholine Acyltransferase 4 ELISA kitLysophosphatidylethanolamine Acyltransferase 2 ELISA kitPlasmalogen Synthase ELISA kitLpcat4 ELISA kitAgpat7 ELISA kitAytl3 ELISA kit |
output | |
Information sourced from Uniprot.org