| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 7.2pg/mL |
| Detection Limit: | 15.6-1000pg/mL |
| Short Description : | This KLb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Klb |
| Gene ID: | 83379 |
| Uniprot ID: | KLOTB_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Present in liver, muscle and white adipose tissue, but not in kidney (at protein level). Expressed in liver and pancreas, and at lower levels in skin, stomach, skeletal muscle, small intestine and lung. |
| Post Translational Modifications | |
| Function | Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21. |
| Protein Name | Beta-Klotho Bkl Betaklotho Klotho Beta-Like Protein |
| Database Links | Reactome: R-MMU-109704 Reactome: -MMU-1257604 Reactome: -MMU-1307965 Reactome: -MMU-5654228 Reactome: -MMU-5654712 Reactome: -MMU-5654719 Reactome: -MMU-5654720 Reactome: -MMU-5654733 Reactome: -MMU-5673001 Reactome: -MMU-6811558 |
| Cellular Localisation | Cell Membrane Single-Pass Type Iii Membrane Protein |
| Alternative ELISA Names | Beta-Klotho ELISA kit Bkl ELISA kit Betaklotho ELISA kit Klotho Beta-Like Protein ELISA kit Klb ELISA kit Betakl ELISA kit |
| output |
Information sourced from Uniprot.org