Tissue Specificity | Expressed in numerous tissues, including brain, spleen, thymus, liver, kidney and testis. |
Post Translational Modifications | Ubiquitinated by RNF5 via 'Lys-63'-linked ubiquitin linkage in a UBE2N-dependent manner. Ubiquitination decreases association with components of the proteasome and ERAD. |
Function | Regulates the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system. |
Protein Name | Jnk1/Mapk8-Associated Membrane ProteinJkampJnk1-Associated Membrane ProteinJampMedulloblastoma Antigen Mu-Mb-50.4 Homolog |
Database Links | |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Jnk1/Mapk8-Associated Membrane Protein ELISA kitJkamp ELISA kitJnk1-Associated Membrane Protein ELISA kitJamp ELISA kitMedulloblastoma Antigen Mu-Mb-50.4 Homolog ELISA kitJkamp ELISA kitJamp ELISA kit |
output | |
Information sourced from Uniprot.org