Mouse ITGa3 (Integrin Alpha 3) Sandwich ELISA Kit Kit (STJE0010081)

Mouse ITGa3 (Integrin Alpha 3) Sandwich ELISA Kit Kit (STJE0010081)

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STJE0010081
$616.28 - $844.43
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.118ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This ITGa3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Itga3
Gene ID: 16400
Uniprot ID: ITA3_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Isoform 1 and isoform 2 are expressed in heart and brain. Only isoform 1 is detected in lung.
Post Translational Modifications
Function Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Protein Name Integrin Alpha-3
Cd49 Antigen-Like Family Member C
Galactoprotein B3
Gapb3
Vla-3 Subunit Alpha
Cd Antigen Cd49c Cleaved Into - Integrin Alpha-3 Heavy Chain - Integrin Alpha-3 Light Chain
Database Links Reactome: R-MMU-210991
Reactome: -MMU-216083
Reactome: -MMU-3000157
Reactome: -MMU-8874081
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Lipid-Anchor
Cell Projection
Invadopodium Membrane
Filopodium Membrane
Enriched Preferentially At Invadopodia
Cell Membrane Protrusions That Correspond To Sites Of Cell Invasion
In A Collagen-Dependent Manner
Alternative ELISA Names Integrin Alpha-3 ELISA kit
Cd49 Antigen-Like Family Member C ELISA kit
Galactoprotein B3 ELISA kit
Gapb3 ELISA kit
Vla-3 Subunit Alpha ELISA kit
Cd Antigen Cd49c Cleaved Into - Integrin Alpha-3 Heavy Chain - Integrin Alpha-3 Light Chain ELISA kit
Itga3 ELISA kit
output

Information sourced from Uniprot.org

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